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November 1, 2004Journal of Bone and Mineral ResearchOpen Access

Secreted Frizzled-Related Protein-1 Inhibits RANKL-Dependent Osteoclast Formation

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Authors

KHK D HauslerNHNicole J. HorwoodYCYoshiro Chuman

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Hausler et al. (2004) studied this question.

synapsesocial.com/papers/6a71e9e935aa2c282ce2ff44https://doi.org/10.1359/jbmr.040807
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Bone Marrow-Derived Stromal Cell Lines MC3T3-G2/PA6 and ST2 Support Osteoclast-Like Cell Differentiation in Cocultures with Mouse Spleen Cells1989 · 497 citations
  2. 2Interleukin-18 (Interferon-γ–inducing Factor) Is Produced by Osteoblasts and Acts Via Granulocyte/Macrophage Colony-stimulating Factor and Not Via Interferon-γ to Inhibit Osteoclast Formation1997 · 376 citations
  3. 3Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL1998 · 4,281 citations
  4. 4A family of secreted proteins contains homology to the cysteine-rich ligand-binding domain of frizzled receptors1997 · 592 citations
  5. 5Interleukin 18 inhibits osteoclast formation via T cell production of granulocyte macrophage colony-stimulating factor.1998 · 221 citations