Single-Procedure Outcomes and Quality-of-Life Improvement 12 Months Post-Cryoballoon Ablation in Persistent Atrial Fibrillation
Why the study?
Does single-procedure cryoballoon ablation improve freedom from arrhythmia and quality of life in patients with persistent atrial fibrillation?
Population
101 patients with persistent atrial fibrillation, mean age 62 ± 11 years, 74% men.
Design
Cohort
Follow-up
12 months
Authors
Discussion
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Member takes
Implication
Single-arm cryoballoon PVI data in early PerAF; leaves open whether PVI-only suffices versus adjunctive lesions in randomized trials.
Structured PICO
Does single-procedure cryoballoon ablation improve freedom from arrhythmia and quality of life in patients with persistent atrial fibrillation?
P
Population
101 patients with persistent atrial fibrillation (100% AF burden confirmed by 18-h Holter or 3 consecutive ECGs), mean age 62 ± 11 years, 74% men.
I
Intervention
Single pulmonary vein isolation (PVI)-only ablation procedure using the second-generation cryoballoon.
O
Outcome
Freedom from AF, atrial flutter, or atrial tachycardia ≥30 s after a 90-day blanking period at 12 months.composite
Single-procedure cryoballoon ablation for persistent atrial fibrillation achieves approximately 61% freedom from arrhythmia at 12 months and significantly improves symptoms and quality of life.
Cite This Study
Bovéda et al. (2018) studied this question.