May 15, 2004Clinical Cancer Research

Expression of Extracellular Matrix Metalloproteases Inducer on Micrometastatic and Primary Mammary Carcinoma Cells

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Population

2,222 breast cancer samples evaluated via high-density tissue microarrays, plus an additional set of 55…

Design

Cohort

Authors

NRNatalie ReimersUniversität Hamburg KZKristine ZafrakasUniversität Hamburg VAVolker AssmannUniversität Hamburg

Discussion

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Implication

EMMPRIN positivity may aid prognostication in breast cancer patients >50 years; hypothesis-generating and requires prospective validation.

Structured PICO

Population

2,222 breast cancer samples evaluated via high-density tissue microarrays, plus an additional set of 55 breast tumors from patients with or without bone marrow micrometastatic cells

Outcome

Correlation of EMMPRIN expression with clinicopathological parameters and tumor-specific survivalsurrogate

EMMPRIN expression in primary breast tumors predicts an unfavorable prognosis and is associated with tumor progression and micrometastasis.

Cite This Study

Reimers et al. (2004) studied this question.

synapsesocial.com/papers/6a71ee59660549caf2c658a1 https://doi.org/10.1158/1078-0432.ccr-03-0610

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Implication

EMMPRIN positivity may aid prognostication in breast cancer patients >50 years; hypothesis-generating and requires prospective validation.

Expression of Extracellular Matrix Metalloproteases Inducer on Micrometastatic and Primary Mammary Carcinoma Cells

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Expression of Extracellular Matrix Metalloproteases Inducer on Micrometastatic and Primary Mammary Carcinoma Cells

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider