Why the study?
Does acute hyperglycemia reduce cerebrovascular reactivity in patients with metabolic syndrome, and is this reduction associated with glycemic variability?
Population
53 subjects, including 18 patients with metabolic syndrome without diabetes mellitus, 9 controls, and 26…
Comparison
Acute hyperglycemia induced by a hyperglycemic… vs Baseline state and patients with established…
Design
Cross-sectional
Authors
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Acute hyperglycemia may heighten cerebrovascular vulnerability in metabolic syndrome; leaves open glycemic variability as a causal factor pending prospective studies.
Does acute hyperglycemia reduce cerebrovascular reactivity in patients with metabolic syndrome, and is this reduction associated with glycemic variability?
Glycemic variability is increased in metabolic syndrome without diabetes and is a major predictor of cerebrovascular reactivity reduction induced by acute hyperglycemia.
Giordani et al. (2014) studied this question.
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