Population
Trypsin-dispersed chick heart cells (ventricles) from 6- to 8-day-old chick embryos
Comparison
In vitro culturing for 1-7 days vs Nondispersed clumps and noncultured intact…
Design
Preclinical
Follow-up
1-7 days
Authors
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Supports cultured chick myocardial cells as in vitro model; leaves open translation to mammalian systems.
Trypsin-dispersed cultured chick myocardial cells retain electrophysiological properties similar to intact hearts, validating their use as an in vitro model.
Lehmkuhl et al. (1963) studied this question.
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