Serological and molecular findings during SARS-CoV-2 infection: the first case study in Finland, January to February 2020

Anu Haveri; Teemu Smura; Suvi Kuivanen; Pamela Österlund; Jussi Hepojoki; Niina Ikonen; Marjaana Pitkäpaasi; Soile Blomqvist; Esa Rönkkö; Anu Kantele; Tomas Strandin; Hannimari Kallio‐Kokko; Laura Mannonen; Maija Lappalainen; Markku Broas; Miao Jiang; Lotta Siira; Mika Salminen; Taneli Puumalainen; Jussi Sane; Merit Melin; Olli Vapalahti; Carita Savolainen‐Kopra

doi:10.2807/1560-7917.es.2020.25.11.2000266

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Abstract

The first case of coronavirus disease (COVID-19) in Finland was confirmed on 29 January 2020. No secondary cases were detected. We describe the clinical picture and laboratory findings 3-23 days since the first symptoms. The SARS-CoV-2/Finland/1/2020 virus strain was isolated, the genome showing a single nucleotide substitution to the reference strain from Wuhan. Neutralising antibody response appeared within 9 days along with specific IgM and IgG response, targeting particularly nucleocapsid and spike proteins.

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Haveri et al. (2020) studied this question.

synapsesocial.com/papers/6a71f40131a3df824329e3b4 https://doi.org/10.2807/1560-7917.es.2020.25.11.2000266

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Serological and molecular findings during SARS-CoV-2 infection: the first case study in Finland, January to February 2020

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Serological and molecular findings during SARS-CoV-2 infection: the first case study in Finland, January to February 2020

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