January 1, 1990Brain Injury

Deep-brain stimulation in a persistent vegetative state: Follow-up results and criteria for selection of candidates

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Why the study?

Does chronic deep-brain stimulation improve recovery in patients in a persistent vegetative state?

Structured PICO

Does chronic deep-brain stimulation improve recovery in patients in a persistent vegetative state?

Population

8 patients in a persistent vegetative state caused by brain damage

Intervention

Chronic deep-brain stimulation (target: mesencephalic reticular formation and/or non-specific thalamic nucleus) for more than 6 months

Outcome

Emergence from persistent vegetative state and ability to communicatehard clinical

Chronic deep-brain stimulation may facilitate emergence from a persistent vegetative state in carefully selected patients.

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May support selected PVS cases; leaves open efficacy pending controlled trials.

Tsubokawa et al. (1990) studied this question.

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