Primary pulmonary lymphoma is a rare entity that should be considered in the differential diagnosis of lung lesions, as its management differs greatly from other lung malignancies.
May support including primary pulmonary lymphoma in lung lesion differentials; single case leaves open broader validation.
In Brief A 69-year-old female smoker presented with dyspnea, anorexia, weight loss, and bone pain. Chest radiography showed a large pulmonary mass. Initial clinical investigations suggested probable metastatic bronchogenic carcinoma, but biopsy revealed that the lesion represented primary pulmonary lymphoma. The pathogenesis of primary pulmonary parenchymal lymphoma is discussed, and differential diagnosis of this entity is reviewed. Primary pulmonary lymphoma is rare, accounting for 1% of all malignant lymphomas. This case report is followed by a brief review of this disease. It emphasizes the importance of recognizing the possibility of primary lung lymphoma in patients presenting with lung lesions as its management greatly differs.
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Gunaratnam et al. (2004) studied this question.
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