Why the study?
Does augmentation with an extracellular matrix graft improve gap formation and tensile failure loads in a human rotator cuff repair model?
Does augmentation with an extracellular matrix graft improve gap formation and tensile failure loads in a human rotator cuff repair model?
Extracellular matrix graft augmentation improves the biomechanical properties of rotator cuff repairs in a human model.
May improve rotator cuff repair biomechanics in models; leaves open whether this improves clinical outcomes.
Despite advances in surgical techniques, 20% to 90% of rotator cuff (RTC) repairs fail. They tend to fail at the suture-tendon junction due to tension at the repair and gap formation prior to healing. This study evaluated the gap formation and ultimate tensile failure loads of a RTC repair with a decellularized human dermal allograft. Augmentation of a RTC repair with an extracellular matrix graft decreased gap formation and increased load to failure in a human RTC repair model.
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Ely et al. (2014) studied this question.
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