Why the study?
Does 1 year of physical training alter norepinephrine kinetics in elderly subjects, and how do different sampling and infusion methods compare for measuring these kinetics?
Population
38 subjects, comprising 17 young (21-28 years) and 21 elderly (60-76 years) individuals.
Comparison
1 year of physical training and methodological… vs Pre-training baseline; young vs. elderly…
Design
Cohort
Follow-up
1 year (for the training subset)
Authors
Loading...
Physical training may not reverse age-related norepinephrine elevation despite fitness gains; leaves open longer interventions while validating [3H]NE over unlabeled methods.
Does 1 year of physical training alter norepinephrine kinetics in elderly subjects, and how do different sampling and infusion methods compare for measuring these kinetics?
Physical training does not reverse the age-associated increase in plasma norepinephrine, and arterialized venous sampling is a practical alternative to arterial sampling for measuring norepinephrine kinetics.
Marker et al. (1994) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: