Why the study?
Masson's tumor in the hand can be particularly challenging to differentiate from other soft-tissue lesions.
Histopathological examination is critical for diagnosing Masson's tumor, as it can closely mimic other soft-tissue lesions like giant cell tumor of the tendon sheath or angiosarcoma.
Histopathology is required to distinguish Masson's tumor from angiosarcoma mimics; this case leaves optimal surveillance protocols open.
Masson's tumor, also known as intravascular papillary endothelial hyperplasia (IPEH), is a rare benign vascular lesion of the skin and subcutaneous tissues. It represents the organization and recanalization of a thrombus within a normal vessel, vascular malformation, or hematoma. Although it can occur in any part of the body, its presence in the hand can be particularly challenging to differentiate from other soft-tissue lesions. We present a case of Masson's tumor located in the distal phalanx of the thumb. Initial magnetic resonance imaging (MRI) examination suggested a giant cell tumor of the tendon sheath; however, following surgical excision, histopathological evaluation confirmed the diagnosis of Masson's tumor. This case highlights the critical importance of histopathological examination, as Masson's tumor can closely mimic other soft-tissue lesions.
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Kastanis et al. (2025) studied this question.
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