Population
Rotavirus SA114S and SA114fM
Design
Preclinical
Authors
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Arg-247 cleavage offers a candidate site for rotavirus intervention; leaves open translation from animal models to human disease.
Trypsin enhances rotavirus infectivity primarily through cleavage of the VP4 protein at the Arg-247 residue.
Arias et al. (1996) studied this question.
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