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December 20, 2011Journal of Surgical OncologyOpen Access

Operative management for recurrent and metastatic adrenocortical carcinoma

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Why the study?

Does surgical resection improve survival in patients with recurrent or metastatic adrenocortical carcinoma?

Population

57 patients who underwent surgical intervention for recurrent or metastatic adrenocortical carcinoma at a…

Design

Cohort

Authors

NDNicole DatriceRLRussell C. LanganRRR. Taylor Ripley

Discussion

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Overview

Metastasectomy may be considered in selected adrenocortical carcinoma with disease-free interval >12 months; leaves open survival benefit versus nonoperative care.

Structured PICO

Does surgical resection improve survival in patients with recurrent or metastatic adrenocortical carcinoma?

P
Population
57 patients who underwent surgical intervention for recurrent or metastatic adrenocortical carcinoma (ACC) at a single tertiary center from 1977 to 2009.
I
Intervention
Surgical resection (metastasectomy) for recurrent or metastatic ACC
O
Outcome
Survival (median and 5-year survival from time of first metastasectomy)hard clinical

Surgical resection of recurrent or metastatic adrenocortical carcinoma may prolong survival, particularly in patients with a disease-free interval greater than 1 year.

Cite This Study

Datrice et al. (2011) studied this question.

synapsesocial.com/papers/6a71fe5b6c240de38cdc47f5https://doi.org/10.1002/jso.23015
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Adrenocortical carcinoma in the United States2008 · 490 citations
  2. 2Radiofrequency ablation of adrenal tumors and adrenocortical carcinoma metastases2003 · 266 citations
  3. 3Adrenal cortical carcinoma in Norway, 1970–19841992 · 101 citations
  4. 4Clinical Features of Adrenocortical Carcinoma, Prognostic Factors, and the Effect of Mitotane Therapy1990 · 719 citations
  5. 5Unique patterns of metastases in common and rare types of malignancy2011 · 33 citations