Population
Cardiac single cell ionic models and experimentally recorded rabbit action potentials
Comparison
Genetic algorithm approach incorporating… vs Genetic algorithm using only action potential…
Design
Preclinical
Authors
Loading...
May improve ionic model parameterization in simulations; leaves open human validation before clinical use.
Incorporating membrane resistance into the objective function of genetic algorithms improves the robustness and convergence of fitting cardiac ionic models, better preserving tissue-level behavior.
Kaur et al. (2014) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: