Long-term oral intake of Panax ginseng improves hypomagnesemia, hyperlactatemia, base deficit, and metabolic acidosis in an alloxan-induced rabbit model.

Figures

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  Figure 1. Effect of Panax ginseng on serum glucose, insulin, and glycated haemoglobin A1c. The data are reported as means±SEMs (n=10). *: P<0.05; **: P<0.01; and ***: P<0.001, paired student’s t-test pre (normal rabbit) vs post (diabetic rabbits); #: P<0.05; ##: P<0.01; and ###: P<0.001, Bonferroni post hoc test following one-way ANOVA post (diabetic) vs 4, 10, and 20 weeks of treatment for glucose, and #: P<0.05; ##: P<0.01; and ###: P<0.001 paired student’s t-test post (diabetic) 20 weeks after treatment for insulin and glycated haemoglobin A1c

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  Figure 2. Effect of Panax ginseng on blood magnesium (Mg2+), lactate, base excess-blood (BE-b), and base excess extra-cellular fluid (BE-ecf). The data are reported as means±SEMs (n=10). *: P<0.05; **: P<0.01; and ***: P<0.001, paired student’s t-test pre (normal rabbit) vs post (diabetic rabbits); #: P<0.05; ##: P<0.01; and ###: P<0.001, Bonferroni post hoc test following one-way ANOVA post (diabetic) vs 4, 10, and 20 weeks of treatment

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  Figure 3. Effect of Panax ginseng on pH, bicarbonate (HCO3-), partial pressure of oxygen (pO2), partial pressure of Carbon dioxide (pCO2). The data are reported as means±SEMs (n=10). *: P<0.05; **: P<0.01; and ***: P<0.001, paired student’s t-test pre (normal rabbit) vs post (diabetic rabbits); #: P < 0.05; ##: P<0.01; and ###: P<0.001, Bonferroni post hoc test following one-way ANOVA post (diabetic) vs 4, 10, and 20 weeks of treatment