Why the study?
Sudden death associated with chagasic malignant arrhythmias is underdiagnosed and its pathophysiological basis is poorly understood.
Population
One 62-year-old woman with non-diagnosed sudden death living in a Chagasic endemic area
Design
Case report
Authors
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Hypothesis-generating in one Chagas case; leaves open mechanistic and clinical relevance pending larger studies.
Histopathological analysis of a sudden death case in a Chagas endemic area revealed complex associations between parasite persistence, sinus disease, micro-ischemia, and neural inflammation, highlighting the need for autopsy protocols in unexplained sudden death.
Héctor O. Rodríguez (2020) studied this question.
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