CHOP (GADD153) and its oncogenic variant, TLS-CHOP, have opposing effects on the induction of G1/S arrest.

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1. 1The <i>gadd</i> and <i>MyD</i> Genes Define a Novel Set of Mammalian Genes Encoding Acidic Proteins That Synergistically Suppress Cell Growth1994 · 120 citations
2. 2Rapid detection of octamer binding proteins with ‘mini extracts’, prepared from a small number of cells1989 · 4,245 citations
3. 3CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription.1992 · 1,196 citations
4. 4Rearrangement of the transcription factor gene <i>CHOP</i> in myxoid liposarcomas with t(12;16)(q13;p11)1992 · 299 citations
5. 5Mammalian genes coordinately regulated by growth arrest signals and DNA-damaging agents.1989 · 689 citations