Why the study?
Does cardiac autonomic regulation, as measured by heart rate variability, differ in children with monosymptomatic nocturnal enuresis compared to healthy controls?
Population
52 children, including 32 with monosymptomatic nocturnal enuresis and 20 healthy age-sex matched controls…
Comparison
24-hour Holter electrocardiogram monitoring for… vs Healthy age-sex matched children undergoing the…
Design
Case-control
Authors
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Parasympathetic hyperactivity may contribute to monosymptomatic nocturnal enuresis; hypothesis-generating and requires prospective validation before clinical consideration.
Does cardiac autonomic regulation, as measured by heart rate variability, differ in children with monosymptomatic nocturnal enuresis compared to healthy controls?
Children with monosymptomatic nocturnal enuresis exhibit significant parasympathetic hyperactivity on 24-hour Holter monitoring compared to healthy controls, suggesting an autonomic role in bladder hyperactivity.
Ünalacak et al. (2004) studied this question.
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