Increased concentration of 99mTc diphosphonate was seen in the breast tissue of 5 patients undergoing bone scans. In one patient, the radiopharmaceutical localized in an advanced primary breast tumor whereas in the other 4, concentration was in normal breast tissue. Accumulation of 99mTc diphosphonate in breast tissue does not indicate breast cancer.
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McDougall et al. (1974) studied this question.
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