Why the study?
The study was conducted to analyze the correlation of lipoprotein(a) with the clinical stability and severity of coronary artery stenosis in patients with coronary artery disease.
Does an elevated lipoprotein(a) level correlate with the presence, clinical instability, and severity of coronary artery stenosis in patients undergoing coronary angiography?
Does an elevated lipoprotein(a) level correlate with the presence, clinical instability, and severity of coronary artery stenosis in patients undergoing coronary angiography?
Elevated lipoprotein(a) is an independent risk factor for coronary artery disease and correlates with both clinical instability and the angiographic severity of coronary stenosis.
May inform CAD risk stratification in observational cohorts; leaves open whether Lp(a) measurement alters management or outcomes.
OBJECTIVE: To analyze the correlation of lipoprotein(a) [Lp(a)] with the clinical stability and severity of coronary artery stenosis in patients with coronary artery disease (CAD). METHODS: =340). In each group, the patients with an established diagnosis of CAD based on coronary angiography findings were further divided into stable angina pectoris (SAP) group and acute coronary syndrome (ACS) group. The correlation between the severity of coronary artery stenosis and Lp(a) was evaluated. RESULTS: =0.006). CONCLUSIONS: Serum level of Lp(a) is an independent risk factor for CAD, and an increased Lp(a) is the residual risk for CAD. In patients with CAD, a high Lp(a) level is associated with the clinical instability and severity of coronary artery stenosis.
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Ma et al. (2019) studied this question.
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