Dilated cardiomyopathy in transgenic mice expressing a mutant A subunit of protein phosphatase 2A

Transgenic mice expressing high levels of a dominant negative mutant of the A subunit (A delta 5) of protein phosphatase 2A (PP2A) in the heart, skeletal muscle, and smooth muscle

Expression of mutant A subunit (A delta 5)

Heart phenotype including heart weight-to-body weight ratio and echocardiographic parameters (dimensions, fractional shortening, wall thickness)surrogate