The major echovirus group is genetically coherent and related to coxsackie B viruses

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Population

Prototype strains of echoviruses (EVs) and coxsackie B viruses (CBVs)

Design

Preclinical

Authors

Discussion

Hypothesis-generating for enterovirus taxonomy; does not yet inform clinical management of EV infections.

Population

Prototype strains of echoviruses (EVs) and coxsackie B viruses (CBVs)

Intervention

Genetic analysis of nucleotide and derived amino acid sequences from different genomic regions (5'UTR, capsid protein-coding and 3D polymerase genes)

Outcome

Genetic homogeneity and evolutionary relationship

Echoviruses and coxsackie B viruses form a single genetically homogeneous cluster, suggesting they diverged relatively late in evolution.

Huttunen et al. (1996) studied this question.

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