Is nebulin the product of Duchenne muscular dystrophy gene?

In October 16th issue of Nature (1986), Louis Kunkel and his associates of Harvard Medical School announced the isolation of the gene the defect of which results in Duchenne muscular dystrophy and showed that its mRNA is as large as 16 kb.l) This suggests that the gene product has a huge molecular weight of more than 500,000. The possible candidate proteins, hitherto known, are nebulin (MW, 700 kDa) and connectin (also called titin; MW, 3000 kDa) in skeletal muscle, as first suggested by Orkin.2>