DURING the course of the therapeutic administration of androgens for various endocrinopathic gynecologic disorders during the past five years, the observation was made that libido was apparently increased in a number of the women being treated (1). Our attention was first drawn to this phenomenon in 1937 by an ovariectomized woman, suffering from the menopause syndrome, who was being treated experimentally with testosterone propionate. During the course of treatment the patient volunteered the information that she had experienced resurgence of sexual desire after a period of quiescence of some ten years. Since then we have been conducting a series of studies to determine the effect of various sterol sex hormones upon the psychosexual reactions of women. The present report is based on our observations of a series of 101 women comprising the following groups. Group A. Twenty-nine cases of primary frigidity which were being treated for some apparently unrelated gynecologic disorder: dysmenorrhea, 6 cases; menometrorrhagia, 16 cases; polymenorrhea, 3 cases; premenstrual tension, 4 cases. Group B.
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Salmon et al. (1943) studied this question.