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Background: Infections caused by Staph. aureus has been recognized as a major challenge incontrolling hospital infections because of it's intense capability of acquiring drug resistance. Regular analysis of antimicrobial susceptibility pattern of Staph.aureus will help to overcome therapeutic difficulties created by rising drug resistance. Objective: This study was conducted to see the current sceptibility pattern of Staph. aureus in wound infection patients of Rajshahi Medical college hospital. Materials and methods: This cross sectional descriptive type of study was conducted in Microbiology department, RMC, Surgery department and it's allied branches, RMCH from January to December, 2019. Staph.aureus were isolated and identified from wound swabs using standardmicrobiological methods and antimicrobial susceptibility test was done by modified Kirby - Bauer disc diffusion method. Results: Total 56 Staph. aureuswere isolated from 172 wound samples. Maximum isolates were from 30-40 years age group and males were affected more than female. Staph. aureus was highly susceptible to linezolid, vancomycin, meropenem and gentamicin. They showed moderate susceptibility to amoxicillin and clavulinic acid, trimethoprim- ulfamethoxazol, ceftriaxone and ciprofloxacin but were highly resistant to penicillin G. Multi drug resistance was found in 27(48.21%) isolates. Conclusions: The resistance rate among Staph. aureus isolatesare increasing. This implicates that Staph. aureus infections should be treated more cautiously and not with penicillin and other ineffective drugs.
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Das et al. (2019) studied this question.
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