What question did this study set out to answer?

To evaluate whether right ventricular myocardial isovolumic relaxation time measured by Doppler tissue imaging correlates with simultaneously measured invasive pulmonary artery systolic pressure.

December 20, 2005Clinical Physiology and Functional Imaging

Right ventricular myocardial isovolumic relaxation time and pulmonary pressure

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Why the study?

Does right ventricular myocardial isovolumic relaxation time derived by Doppler tissue imaging correlate with invasively measured pulmonary artery systolic pressure?

Key Points

To evaluate whether right ventricular myocardial isovolumic relaxation time measured by Doppler tissue imaging correlates with simultaneously measured invasive pulmonary artery systolic pressure.
Simultaneously performed Doppler echocardiography, including pulsed Doppler tissue imaging, and invasive cardiac catheterization in 26 consecutive patients (18 males, mean age 52 ± 12 years).
Measured right ventricular myocardial isovolumic relaxation time (IVRt) at basal and mid cavity segments of the free wall, correcting for heart rate (IVRt/RR%), alongside invasive right atrial and pulmonary artery pressures.
Heart rate-corrected IVRt significantly correlated with pulmonary artery systolic pressure at both the basal segment (r = 0.42, P < 0.05) and mid cavity segment (r = 0.71, P < 0.001).
In patients with normal right atrial pressure (<7 mmHg), correlation with pulmonary artery systolic pressure improved at both the basal (r = 0.74, P < 0.05) and mid cavity segments (r = 0.83, P < 0.01).

Structured PICO

Does right ventricular myocardial isovolumic relaxation time derived by Doppler tissue imaging correlate with invasively measured pulmonary artery systolic pressure?

Population

26 consecutive patients undergoing simultaneous Doppler echocardiography and cardiac catheterization, mean age 52 +/- 12 years, 18 males.

Intervention

Right ventricular myocardial isovolumic relaxation time (IVRt) derived by pulsed Doppler tissue imaging (DTI), corrected for heart rate.

Comparator

Simultaneously measured invasive pulmonary artery systolic pressure (PASP) via cardiac catheterization.

Outcome

Correlation between DTI-derived IVRt/RR% and invasive PASP.surrogate

Pulsed Doppler tissue imaging-derived right ventricular isovolumic relaxation time correlates well with invasively measured pulmonary artery systolic pressure, offering a non-invasive assessment tool.

Discussion

No takes yet. Share an insight, caveat, or question.

Implication

May support non-invasive PASP estimation via regional IVRT; leaves open prospective validation before clinical use.

Cite This Study

Lindqvist et al. (2005) studied this question.

synapsesocial.com/papers/6a722a1a8031ec7bb1dd4344 https://doi.org/10.1111/j.1475-097x.2005.00639.x

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Right ventricular myocardial isovolumic relaxation time and pulmonary pressure

Key Points

Structured PICO

Discussion

Implication

Cite This Study

Right ventricular myocardial isovolumic relaxation time and pulmonary pressure

Key Points

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Also Consider