Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
September 15, 2021Open Access

Effectiveness of Interventions To Enable Hypertension Medication Adherence In Low-And Middle-Income Countries: A Systematic Review And Meta-analysis

View Full Paper
Ask AI
Bookmark
Share

Why the study?

Hypertension is increasing in LMICs, and antihypertensive medication adherence is crucial to controlling blood pressure, prompting an evaluation of non-pharmacological interventions.

Do non-pharmacological interventions improve blood pressure control and medication adherence in hypertensive patients in low- and middle-income countries?

Population

Patients with hypertension aged 18-75 years across 14 RCTs in LMICs

Comparison

Non-pharmacological interventions vs control

Design

Systematic review and meta-analysis of randomised controlled trials

Authors

ONOlivia NakwafilaUniversity of NamibiaBSBenn SartoriusThe University of QueenslandSNSphamandla Josias NkambuleUniversity of KwaZulu-Natal

Discussion

Loading...

Member takes

Implication

Non-pharmacological interventions improve adherence and BP control in LMIC hypertension; extends evidence for scalable strategies in resource-limited settings.

Structured PICO

Do non-pharmacological interventions improve blood pressure control and medication adherence in hypertensive patients in low- and middle-income countries?

P
Population
Hypertensive patients aged 18-75 years in low- and middle-income countries (LMICs). 14 randomized controlled trials included.
I
Intervention
Non-pharmacological interventions to improve blood pressure medication adherence (including educational interventions directed to the patient or health professional, self-monitoring, appointment reminder systems, and organisational interventions aimed at delivery care).
C
Comparator
Control groups (standard care as defined by individual included trials).
O
Outcome
Changes in mean systolic blood pressure (SBP) and mean diastolic blood pressure (DBP).surrogate

Non-pharmacological interventions, particularly educational strategies and appointment reminders, significantly improve blood pressure control and medication adherence among hypertensive patients in low- and middle-income countries.

Limitations

  • High heterogeneity across studies due to different study periods, sample sizes, and pooling of multi-component interventions
  • Inconsistency
  • Publication bias

Cite This Study

Nakwafila et al. (2021) studied this question.

synapsesocial.com/papers/6a72304f5d37378ac1df124bhttps://doi.org/10.21203/rs.3.rs-856012/v1
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Interventions for improving adherence to treatment in patients with high blood pressure in ambulatory settings2004 · 299 citations
  2. 2Nonpharmacologic Interventions for Reducing Blood Pressure in Adults With Prehypertension to Established Hypertension2020 · 186 citations
  3. 3Assessing Adherence to Antihypertensive Therapy in Primary Health Care in Namibia: Findings and Implications2017 · 89 citations
  4. 4Smartphone and social media-based cardiac rehabilitation and secondary prevention in China (SMART-CR/SP): a parallel-group, single-blind, randomised controlled trial2019 · 177 citations
  5. 5Journal of The American College of Cardiology2015 · 2,619 citations