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January 15, 2008Cancer ResearchOpen Access

Inhibition of Hsp90 Down-regulates Mutant Epidermal Growth Factor Receptor (EGFR) Expression and Sensitizes EGFR Mutant Tumors to Paclitaxel

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Authors

ASAyana SawaiMemorial Sloan Kettering Cancer CenterSCSarat ChandarlapatyMemorial Sloan Kettering Cancer CenterHGHeidi GreulichBroad Institute

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Sawai et al. (2008) studied this question.

synapsesocial.com/papers/6a72316984cc45bb7be014b3https://doi.org/10.1158/0008-5472.can-07-1570
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  5. 5BCR-ABL point mutants isolated from patients with imatinib mesylate–resistant chronic myeloid leukemia remain sensitive to inhibitors of the BCR-ABL chaperone heat shock protein 902002 · 277 citations