This study reevaluates the clinicopathologic behavior of fibrosarcoma using current diagnostic criteria to correlate histologic grade and stage with survival and metastasis.
May refine fibrosarcoma prognostication with modern criteria; leaves open validation in prospective cohorts.
Over the last 20 to 30 years, a recognition and general acceptance of the entity of malignant fibrous histiocytoma and monophasic synovial sarcoma has occurred. The introduction of these diagnostic categories among the generic group of spindle cell sarcomas now requires a reevaluation of the more traditional and historic entity of fibrosarcoma and the clinical ramification of this diagnosis. A review of 132 cases of fibrosarcoma using current diagnostic criteria was undertaken to clarify the behavior of fibrosarcoma as diagnosed in current patients. Special attempts were made to correlate histologic grade and Enneking stage in fibrosarcomas in an effort to correlate their predictive value in metastatic rate and survival.
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Scott et al. (1989) studied this question.
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