A simple, sensitive, rapid, accurate, and precise spectrophotometric method has been developed for estimation of gatifloxacin in pharmaceutical dosage forms. The method is based on formation of orange coloured chromogen due to reaction of gatifloxacin with ferric nitrate reagent solution, which exhibits maximum absorption at 470 nm against blank. Stability of chromogen was found up to 1 h, and chromogen obeyed linearity over 20-200 µg/ml.
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Kuchekar et al. (2006) studied this question.
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