ASFV disrupts the trans-Golgi network in a microtubule-dependent manner, slowing the delivery of membrane proteins like MHC class I to the cell surface, which may serve as an immune evasion mechanism.
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ASFV may enable immune evasion by downregulating MHC class I; leaves open in vivo relevance and vaccine implications.
Netherton et al. (2006) studied this question.
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