Why the study?
Carotid endarterectomy reduces stroke risk and improves cerebral perfusion, but the utility of assessing pulsatile blood volume and flow during the procedure required investigation.
Does combined near-infrared spectroscopy/diffuse correlation spectroscopy detect alterations in pulsatile hemodynamics in patients undergoing carotid endarterectomy?
Does combined near-infrared spectroscopy/diffuse correlation spectroscopy detect alterations in pulsatile hemodynamics in patients undergoing carotid endarterectomy?
Analysis of pulsatile hemodynamic signals using NIRS/DCS during CEA can detect ipsilateral alterations, potentially enabling the discovery of non-invasive biomarkers for cortical perfusion.
Carotid endarterectomy (CEA) involves removal of plaque in the carotid artery to reduce the risk of stroke and improve cerebral perfusion. This study aimed to investigate the utility of assessing pulsatile blood volume and flow during CEA. Using a combined near-infrared spectroscopy/diffuse correlation spectroscopy instrument, pulsatile hemodynamics were assessed in 12 patients undergoing CEA. Alterations to pulsatile amplitude, pulse transit time, and beat morphology were observed in measurements ipsilateral to the surgical side. The additional information provided through analysis of pulsatile hemodynamic signals has the potential to enable the discovery of non-invasive biomarkers related to cortical perfusion.
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Zavriyev et al. (2023) studied this question.
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