Why the study?
Does tiotriazoline improve exercise tolerance and cardioprotective molecular effects in patients with stable angina?
Does tiotriazoline improve exercise tolerance and cardioprotective molecular effects in patients with stable angina?
Tiotriazoline added to complex therapy may improve exercise tolerance, reduce angina attacks, and provide cardioprotective effects in patients with stable ischemic heart disease.
Answers are grounded in this paper and cite their sources.
Tiotriazoline may benefit stable angina; leaves open efficacy and role pending randomized trials.
Aim. To study molecular effects of tiotriazoline in 30 patients with stable angina I-III functional class. Material and methods. Comparison of molecular effects of cardioprotection is done based on dynamics of exercise tolerance dynamics, and via proteomic methods of investigation, questionnaires assessment of life quality in patients with ischemic heart disease (IHD). Results. It was found, that tiotriazoline improves exercise tolerance, shows strong cardioprotective effect that includes antioxidant and cytoprotection effects in IHD patients. Conclusion. Tiotriazoline helps to reduce the mean number of angina attacks in IHD patients, as to improve mean functional class.
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Карташова et al. (2016) studied this question.
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