Cardioprotective Effects of Metabolic Therapy in Patients With Ischemic Heart Disease: Analysis of Digital Processing of Electrocardiograms Using the Software Complex "Smart Ecg"

Objective. In order to determine the cardioprotective effect of metabolic therapy, the results of digital processing of the standard ECG in patients with coronary heart disease were analyzed using the own Smart ECG software with the evaluation of the effect of drugs (tyvortin, trivorel, tiotriazoline, corvitine) with antiarrhythmic anticipation, in comparison with the effects of amiodarone and bisoprolol on the main parameters of HRD and dispersion of the QT interval, the angle of inclination of the ST segment and the results of the analysis differentiated T wave.Results and conclusions. The possibility of an effective quantitative evaluation of the electrocardiogram with its digital processing (digitalization) with the use of its own Smart-ECG software in patients with stable angina pectoris was proved. In the complex analysis of effects because of the use of drugs, it was found that tivortin / tyvorel reduced the risk of adverse events with stable angina pectoris and activated parasympathetic contour, corvitine and thiotriazoline - reduced the dispersion of the QT interval, thiotriazoline, corvitine and tyvortin, accelerated transient depression of the ST segment - reducing the risk of coronary heart disease and increasing antiarrhythmic effect. Bisoprolol and amiodarone increase the SDNN score and consequently reduce the risk of adverse events with stable angina pectoris, amiodarone stimulates the activation of the parasympathetic contour and less efficiently affects ST slope than bisoprolol, both drugs slightly optimize the ratio of maximum velocities and thus maintain anti-ischemic status.