What question did this study set out to answer?

To quantitatively evaluate postextrasystolic potentiation and left ventricular contractile enhancement in normal and failing human hearts using catheter-tip manometer readings.

May 1, 1975Cardiovascular Research

Quantitative evaluation of postectopic beats in the normal and failing human heart using indices derived from catheter-tip manometer readings

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Why the study?

Is postextrasystolic potentiation of left ventricular contraction altered in patients with cardiomyopathy compared to those with normal hearts?

Population

Patients with and without cardiomyopathy

Comparison

Measurement of postextrasystolic potentiation… vs Patients without cardiomyopathy (normal heart)

Design

Cross-sectional

Authors

JKJ KvasničkaÇevre ve Şehircilik Bakanlığı BLBo LianderSahlgrenska University Hospital HBH. BromanUniversity of Vermont

Discussion

Member takes

Implication

Supports altered postextrasystolic potentiation in cardiomyopathy; leaves open its prognostic or therapeutic relevance pending prospective studies.

Key Points

To quantitatively evaluate postextrasystolic potentiation and left ventricular contractile enhancement in normal and failing human hearts using catheter-tip manometer readings.
Recorded left ventricular hemodynamic indices using a high-fidelity catheter-tip manometer.
Evaluated contractile responses following postectopic beats in patients with cardiomyopathy and in control subjects without cardiomyopathy.
Postextrasystolic potentiation elicited an enhancement of left ventricular contraction across examined subjects.
Patients with cardiomyopathy exhibited a greater degree of postectopic left ventricular contraction enhancement relative to non-cardiomyopathy controls.

Structured PICO

Is postextrasystolic potentiation of left ventricular contraction altered in patients with cardiomyopathy compared to those with normal hearts?

Population

Patients with and without cardiomyopathy

Intervention

Measurement of postextrasystolic potentiation using a catheter-tip manometer

Comparator

Patients without cardiomyopathy (normal heart)

Outcome

Enhancement of left ventricular contraction (postextrasystolic potentiation)surrogate

Postextrasystolic potentiation of left ventricular contraction is increased in patients with cardiomyopathy compared to normal hearts.

Cite This Study

Kvasnička et al. (1975) studied this question.

synapsesocial.com/papers/6a724500febe604dd70a8425 https://doi.org/10.1093/cvr/9.3.336

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Implication

Supports altered postextrasystolic potentiation in cardiomyopathy; leaves open its prognostic or therapeutic relevance pending prospective studies.

Quantitative evaluation of postectopic beats in the normal and failing human heart using indices derived from catheter-tip manometer readings

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Quantitative evaluation of postectopic beats in the normal and failing human heart using indices derived from catheter-tip manometer readings

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Also Consider