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different tACS frequencies were applied over the M1 in healthy participants.One of the critical factors that may lead to the distinct outcome is the different stimulation sites used.The results provided strong evidence that applying tACS at the hotspot and C3 does indeed modulate the corticospinal tract differently and that applying tACS at the conventionally used C3 site may yield weak or no modulation effects for both online and offline measures.
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Couture et al. (2025) studied this question.
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