The occurrence of Pneumocystis carinii pneumonia and progressive vaccinia in siblings, asso- ciated with hypogammaglobulinaemia, has already been recorded (McKay and Richardson, 1959). A similar combination in siblings described here seems worthy of record, because the gamma globulin value in the sib with progressive vaccinia was pro- bably within normal limits, and in both patients there seems to have been a failure of maturation of lymphocytes.
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Allibone et al. (1964) studied this question.
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