What question did this study set out to answer?

To describe the histological, ultrastructural, and functional organization of the normal human ureter, focusing on muscle bundles, cellular junctions, and innervation.

December 1, 1976The Journal of Urology

Ureteral Structure and Ultrastructure. Part I. The Normal Human Ureter

View Full Paper

Ask AI

Bookmark

Authors

MHMoneer K. HannaCornell University RJRobert D. JeffsUniversity of Maryland, Baltimore JSJennifer M. SturgessHospital for Sick Children

Discussion

Member takes

Implication

Histological analysis reveals non-layered muscle architecture and potential pacemaker cells in human ureters, highlighting cellular mechanisms of urinary tract peristalsis.

Key Points

To describe the histological, ultrastructural, and functional organization of the normal human ureter, focusing on muscle bundles, cellular junctions, and innervation.
Examined 28 normal human ureters using light and electron microscopy.
Conducted microdissections of 3 uretero-trigonal units to evaluate anatomical architecture.
Revealed that the ureter is a non-layered muscular tube formed by bundles of heterogeneously oriented smooth muscle cells functionally coupled by nexus junctions.
Identified morphologically distinct muscle cells that likely serve as ureteral pacemakers and demonstrated observable structural variations between contracted and relaxed cell states.
Characterized the ultrastructural features of the normal urothelial lining alongside both adrenergic and cholinergic neural elements.

Cite This Study

Hanna et al. (1976) studied this question.

synapsesocial.com/papers/6a724c50a7fbea1e4408a2aa https://doi.org/10.1016/s0022-5347(17)58986-7

View Full Paper

Ask AI

Bookmark

Implication

Histological analysis reveals non-layered muscle architecture and potential pacemaker cells in human ureters, highlighting cellular mechanisms of urinary tract peristalsis.

Ureteral Structure and Ultrastructure. Part I. The Normal Human Ureter

Discussion

Member takes

Implication

Key Points

Cite This Study

Ureteral Structure and Ultrastructure. Part I. The Normal Human Ureter

Discussion

Member takes

Implication

Key Points

Cite This Study

Also Consider

Also Consider