aplastic anaemia is characterised by anaemia, leuco- penia, and thrombocytopenia.The defect is cellular with an increased tendency to infection and bleeding.4Although prejudicial to the success of skin grafting, it is not a contraindication provided deficiencies are corrected perioperatively, haemostasis is achieved before grafting, and the formation of haematoma is avoided afterwards.Each of these children had a chronic cutaneous manifestation ofa haematological or immunodeficiency disease.Healing was assumed to be abnormal because of a defect in either humoral or cellular defence mechanisms.This assumption delayed referral for surgery by some months in each case, but debridement followed by split skin grafting produced rapid healing.
No takes yet. Share an insight, caveat, or question.
Turner et al. (1990) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: