Why the study?
CAD is the leading cause of death in the United States, making optimal diagnostic modalities essential for the diagnosis, prognostication, and follow-up of patients.
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Design
Review
CCTA plaque evaluation may refine CAD assessment; leaves open its prognostic value and practice integration pending higher-level evidence.
Coronary artery disease (CAD) is the leading cause of death in the United States in both men and women (1). It is therefore crucial to have optimal diagnostic modalities for diagnosis, prognostication and follow up of CAD patients. Coronary computed tomography angiography (CCTA) is advantageous in its ability to delineate coronary anatomy, including evaluation of the arterial lumen and surrounding atherosclerotic plaque to identify presence and severity of CAD. CCTA also allows evaluation of plaque composition and identifying those with high risk features (2). In addition, the inference of the physiologic, flow-limiting significance of anatomically detected lesions is possible, further aiding clinical decision making for physicians (3-5).
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Kyung et al. (2020) studied this question.