Effects of Blood Pressure Reduction in Mild Hypertension

Letters7 July 2015Effects of Blood Pressure Reduction in Mild HypertensionStephen A. Martin, MD, EdMStephen A. Martin, MD, EdMFrom University of Massachusetts Medical School, Barre, Massachusetts.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/L15-5103 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:Sundström and colleagues (1) conclude that drug treatment “in the primary preventive setting is likely to reduce the risk for several important adverse health outcomes.” This finding is interesting given that the 2012 Cochrane review that they cite (2) found no evidence of mortality or morbidity benefit with drug treatment of mild hypertension. What changed?The authors explain the different conclusions by stating, “Besides the inclusion of persons with diabetes or prior antihypertensive treatment, the disparity between the conclusions of this review and the one immediately preceding it is primarily attributable to statistical power. The present review ...References1. Sundström J, Arima H, Jackson R, Turnbull F, Rahimi K, Chalmers J, et al; Blood Pressure Lowering Treatment Trialists' Collaboration. Effects of blood pressure reduction in mild hypertension: a systematic review and meta-analysis. Ann Intern Med. 2015;162:184-91. [PMID: 25531552] doi:10.7326/M14-0773 LinkGoogle Scholar2. Diao D, Wright JM, Cundiff DK, Gueyffier F. Pharmacotherapy for mild hypertension. Cochrane Database Syst Rev. 2012;8:CD006742. [PMID: 22895954] doi:10.1002/14651858.CD006742.pub2 CrossrefMedlineGoogle Scholar3. Martin SA, Boucher M, Wright JM, Saini V. Mild hypertension in people at low risk. BMJ. 2014;349:g5432. [PMID: 25224509] doi:10.1136/bmj.g5432 CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: From University of Massachusetts Medical School, Barre, Massachusetts.Disclosures: Authors have disclosed no conflicts of interest. Forms can be viewed at www.acponline.org/authors/icmje/ConflictOfInterest Forms.do?msNum=L15-0234. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoEffects of Blood Pressure Reduction in Mild Hypertension Johan Sundström , Hisatomi Arima , Rod Jackson , Fiona Turnbull , Kazem Rahimi , John Chalmers , Mark Woodward , Bruce Neal , and Effects of Blood Pressure Reduction in Mild Hypertension Johan Sundström , Hisatomi Arima , Rod Jackson , Fiona Turnbull , Kazem Rahimi , John Chalmers , Mark Woodward , Bruce Neal , and Effects of Blood Pressure Reduction in Mild Hypertension Johan Sundström and Bruce Neal Effects of Blood Pressure Reduction in Mild Hypertension Johan Sundström and Bruce Neal Metrics 7 July 2015Volume 163, Issue 1Page: 67KeywordsBlood pressureConflicts of interestDisclosureDrugsHeart failureHypertensionMorbidityMyocardial infarction ePublished: 7 July 2015 Issue Published: 7 July 2015 Copyright & PermissionsCopyright © 2015 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...