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Of forty-seven patients with histologically proven myeloma of the spine, thirty-three had multiple lesions at the time of the first examination and fourteen were solitary. 2. Five of the solitary cases, in which the patients are alive and well without signs of dissemination four to fourteen years after diagnosis, are considered in detail and the differences in clinical presentation and prognosis are discussed. 3. A sixth case, described in detail, showed scattered osteolytic lesions after ten years.
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Valderrama et al. (1968) studied this question.
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