January 1, 1988Journal of Biological ChemistryOpen Access

Severin, gelsolin, and villin share a homologous sequence in regions presumed to contain F-actin severing domains.

View Full Paper

Ask AI

Bookmark

Population

Dictyostelium discoideum cDNA library

Design

Preclinical

Authors

EAE. AndréNorwegian Womens Public Health Association FLF. LottspeichUniversity of Hohenheim MSMichael SchleicherGoethe University Frankfurt

Discussion

Member takes

Implication

Does not inform clinical practice; leaves open functional conservation of severin in mammalian cardiac actin regulation.

Structured PICO

Population

Dictyostelium discoideum cDNA library

Intervention

cDNA cloning and sequencing of severin

Outcome

Amino acid sequence of severin and homology to villin and gelsolin

Severin shares a homologous sequence with gelsolin and villin in regions presumed to contain F-actin severing domains, suggesting a common evolutionary origin.

Cite This Study

André et al. (1988) studied this question.

synapsesocial.com/papers/6a72577aa528af2d65c46413 https://doi.org/10.1016/s0021-9258(19)35412-2

View Full Paper

Ask AI

Bookmark

Severin, gelsolin, and villin share a homologous sequence in regions presumed to contain F-actin severing domains.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Severin, gelsolin, and villin share a homologous sequence in regions presumed to contain F-actin severing domains.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider