Why the study?
Does the presence of Type 2 Diabetes Mellitus affect the clinical risk factors and angiographic severity in patients with acute coronary syndrome?
Does the presence of Type 2 Diabetes Mellitus affect the clinical risk factors and angiographic severity in patients with acute coronary syndrome?
In patients with acute coronary syndrome, the presence of type 2 diabetes is associated with a higher prevalence of multivessel disease, hypertension, elevated triglycerides, and higher CRP levels.
May inform ACS risk stratification in T2DM; leaves open whether these associations are causal or warrant targeted interventions.
Background: Diabetes mellitus (DM) is equivalent as well a risk factor of cardiovascular disease.We analyzed the effects of DM on clinical risk factors of acute coronary syndrome by comparing DM group with Non-DM group.Methods: A total of 847 (514 males and 333 females) patients with acute coronary syndrome was selected from 1664 patients who had undergone coronary angiography (CAG).These patients comprised 105 subjects with non-ST elevation myocardial infarction (MI), 313 with ST elevation MI and 429 with unstable angina.According to the presence of DM, we retrospectively reviewed the measured basic demographics, biochemical markers and coronary angiographic findings.Results: In the multivariated analysis, history of hypertension (P = 0.001), C-reactive protein (CRP) level (P = 0.001) and triglyceride level (P = 0.018) were independent risk factors in type 2 diabetic group.Also the frequency of multiple coronary vessel disease was higher in DM group than non-DM group on the coronary angiographic finding Conclusions: Classic risk factors for acute coronary syndrome are strong predictors in patients with type 2 DM.Among these factors, the most important powerful risk factor is history of hypertension.(
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Moon et al. (2006) studied this question.
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