Pre-existent depression in the 2 weeks before an acute coronary syndrome can be associated with delayed presentation of the heart attack
Why the study?
Does pre-existent depression delay presentation and alter treatment compliance in patients with acute coronary syndrome?
Population
276 consecutive patients with acute coronary syndrome, including 68 with ST elevation myocardial infarction.
Comparison
Pre-existent depression in the 2 weeks prior to… vs No pre-existent depression (BDI score < 10).
Design
Cohort
Authors
Discussion
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Member takes
Implication
Depression may delay ACS presentation; leaves open effects on compliance and need for prospective trials.
Structured PICO
Does pre-existent depression delay presentation and alter treatment compliance in patients with acute coronary syndrome?
P
Population
276 consecutive patients with acute coronary syndrome (ACS), including 68 with ST elevation myocardial infarction (MI).
I
Intervention
Pre-existent depression (Beck Depression Inventory [BDI] score >= 10) in the 2 weeks prior to presentation.
C
Comparator
No pre-existent depression (BDI score < 10).
O
Outcome
Time delay to seeking help (time from onset of the predominant symptom to seeking help).patient reported
Pre-existent depression is associated with a significant delay in seeking help for acute coronary syndrome symptoms.
Cite This Study
Wong et al. (2008) studied this question.