October 15, 2010Critical Care Medicine

Dexmedetomidine-related atrial standstill and loss of capture in a pediatric patient after congenital heart surgery

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Why the study?

Does dexmedetomidine cause loss of atrial capture in pediatric patients with predisposing conduction abnormalities and pacemakers?

Population

A 3-year-old girl admitted to the pediatric intensive care unit after mitral valve replacement for…

Design

Case_report

Authors

SSSuzanne ShepardUniversity of California, San Diego STShai Tejman‐YardenBen-Gurion University of the Negev SKSandeep KhannaProtagonist Therapeutics (United States)

Discussion

Member takes

Implication

May warrant caution with dexmedetomidine in pediatric pacemaker patients; hypothesis-generating and requires prospective confirmation.

Structured PICO

Does dexmedetomidine cause loss of atrial capture in pediatric patients with predisposing conduction abnormalities and pacemakers?

Population

A 3-year-old girl admitted to the pediatric intensive care unit after mitral valve replacement for persistent severe mitral insufficiency, with a history of tetralogy of Fallot, mitral and tricuspid valve repair, pulmonary valve replacement, maze procedure, sinus node dysfunction, and permanent epicardial dual-chamber pacemaker.

Intervention

Dexmedetomidine infusion at 0.6 mcg/kg/hr initiated on postoperative day two.

Outcome

Unsuccessful atrial capture (atrial standstill) observed on pacemaker interrogation.safety

Dexmedetomidine administration may cause atrial standstill and loss of capture in pediatric patients with predisposing conduction abnormalities and pacemakers, warranting caution in this population.

Cite This Study

Shepard et al. (2010) studied this question.

synapsesocial.com/papers/6a725fb784cc45bb7be01c81 https://doi.org/10.1097/ccm.0b013e3181feb4b3

Topics

Mitral valve intervention Congenital heart disease adults

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Dexmedetomidine-related atrial standstill and loss of capture in a pediatric patient after congenital heart surgery

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

Dexmedetomidine-related atrial standstill and loss of capture in a pediatric patient after congenital heart surgery

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider