Why the study?
Does an optimized defibrillation waveform with a short preceding pulse improve defibrillation efficacy in animal models?
Does an optimized defibrillation waveform with a short preceding pulse improve defibrillation efficacy in animal models?
A short, high-voltage pulse preceding a defibrillation pulse significantly improves defibrillation efficacy in animal models, likely by enhancing electroporation.
Short-pulse waveform improves swine defibrillation; leaves open translation to human VF or survival benefit.
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Malkin et al. (2006) studied this question.
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