April 1, 2002Arteriosclerosis Thrombosis and Vascular Biology

Contribution of Hepatic Lipase, Lipoprotein Lipase, and Cholesteryl Ester Transfer Protein to LDL and HDL Heterogeneity in Healthy Women

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Population

120 normolipidemic, nondiabetic, premenopausal women

Design

Cohort

Authors

MCMolly C. CarrEli Lilly (United States)AAAmir F. AyyobiRoyal Columbian Hospital SMSusan J. MurdochBabraham Institute

Discussion

Member takes

Implication

Hypothesis-generating for lipase modulation of LDL buoyancy in women; prospective trials needed before clinical consideration.

Structured PICO

Population

120 normolipidemic, nondiabetic, premenopausal women

Outcome

Small dense LDL (sdLDL) and HDL subspecies (LDL buoyancy, HDL2 cholesterol, HDL3 cholesterol)surrogate

Hepatic lipase activity and its gene promoter polymorphism play a significant role in determining LDL and HDL heterogeneity in healthy women without hypertriglyceridemia.

Cite This Study

Carr et al. (2002) studied this question.

synapsesocial.com/papers/6a72635084cc45bb7be01d23 https://doi.org/10.1161/01.atv.0000013284.47317.95

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Contribution of Hepatic Lipase, Lipoprotein Lipase, and Cholesteryl Ester Transfer Protein to LDL and HDL Heterogeneity in Healthy Women

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Contribution of Hepatic Lipase, Lipoprotein Lipase, and Cholesteryl Ester Transfer Protein to LDL and HDL Heterogeneity in Healthy Women

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider