Pattern of Pulsed Wave Tissue Doppler Imaging of Anterior Wall of Ascending Aorta in Patients with Premature Coronary Artery Disease in Relation to Aortic Stiffness Index Parameters

Atherosclerosis and arterial stiffening may coexist and the relations of these parameters in patients with premature coronary artery disease (CAD) have not been well elucidated. Tissue Doppler imaging of the ascending aorta may be used in the assessment of elastic properties. A number of studies pointed that increased aortic stiffness (AS) is considered as a predictor index of cardiovascular disease (CVD) morbidity and mortality. Besides, a genetic factor was proposed to play a role based on the finding that increased arterial stiffness was found to be more prevalent in individuals with positive family history of premature coronary artery disease. Our study hypothesize that there’s a correlation between CAD in males younger than 45 years old and females younger than 55 years old in one hand and the aortic wall velocities assessed by TDI echocardiography on the other hand.