Key result
Aortic stiffening measured by pulse wave velocity did not predict the presence of coronary calcium or extracoronary atheroma in asymptomatic men at cardiovascular risk.
Why the study?
Does aortic wall stiffness predict coronary and extracoronary atherosclerosis in asymptomatic men at risk for cardiovascular disease?
Population
190 asymptomatic men at risk for cardiovascular disease
Design
Cross-sectional
Authors
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PWV should not guide subclinical atherosclerosis screening in at-risk men; leaves open its prognostic role in prospective cohorts.
Cross-Sectional (n=190)
Does aortic wall stiffness predict coronary and extracoronary atherosclerosis in asymptomatic men at risk for cardiovascular disease?
Aortic stiffening does not predict the presence of coronary and extracoronary atheroma in asymptomatic men and is not a useful surrogate marker of early atherosclerosis.
J.L. Megnien (1998) conducted a cross-sectional in Asymptomatic cardiovascular risk (n=190). Aortic wall stiffness measurement (PWV, C, Ci) was evaluated on Association of aortic wall stiffness with coronary calcium deposit, extent of extracoronary plaque, and estimated Framingham coronary risk. Aortic stiffening measured by pulse wave velocity did not predict the presence of coronary calcium or extracoronary atheroma in asymptomatic men at cardiovascular risk.
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